Oprah Closes Chicago Based Harpo Studios! So here are the facts Oprah’s four-building Harpo Studios will close its doors in Chicago’s West Loop in December after 26 years ,she sold the 3.5-acre campus to a developer last year for $32 million and only a few of her 200 Chicago workers will be joining her 140-person LA staff. Wow even Oprah is downsizing.Find out why after the jump.