Spending lots of free time glued to the TV or computer screen can hurt your heart and shorten your life, no matter how much exercise you get when you’re not riding the couch, a new study suggests. So yes, watch your Thanksgiving football but after – turn the TV off and enjoy the fam!

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Health – People who spent at least four hours per day watching TV, playing video games, or using a computer for fun were more than twice as likely as those who kept their recreational “screen time” under two hours to experience a heart attack,stroke, or other serious cardiovascular problem, the study found. Couch potatoes were also about 50% more likely to die of any cause during the four-year study.

The link between screen time and heart problems barely changed when the researchers factored in the amount of moderate-to-vigorous exercise the study participants did, suggesting that the health benefits of exercise don’t cancel out all that time in front of the tube or computer. (The researchers also controlled for obesity, smoking, diabetes, social class, and other factors.)

The study doesn’t prove that watching TV or playing computer games is inherently unhealthy, says the lead researcher, Emmanuel Stamatakis, PhD, an epidemiologist at University College London, in the U.K. The real culprit may be what people tend to do during those activities: sit.

Why is sitting harmful? It’s not entirely clear, but animal studies have shown that prolonged sitting slows down the action of an enzyme (lipoprotein lipase) that breaks down fats in the blood, such as cholesterol and triglycerides. When the enzyme activity slows, levels of those substances climb. This is a “very plausible explanation” for the findings, Stamatakis says.

The study, which appears in the January 18 issue of the Journal of the American College of Cardiology, adds to a growing body of evidence that “prolonged sitting is bad for health,” says Barry Braun, PhD, director of the Energy Metabolism Laboratory at the University of Massachusetts Amherst.

“Too much sitting is not the same thing as too little exercise,” says Braun, who studies the effects of exercise and inactivity on the body but was not involved in the new research. “Public health recommendations that have primarily focused on adding physical activity also need to urge subtracting time spent sitting.”